I have started this area to collect the latest PubMed? articles on items of interest. If you have a topic that you would like to see listed here, please either add the information as a comment to this page, or via the discussion forum. You can access either area by clicking on the "comment" or "discuss" tabs. I hope you will find this useful as a bench tool for quick reference. It can also provide a quick way to browse the literature. (JSullinger)
PubMed: p16 and CIN. Discuss here.
- A cocktail of MCM2 and TOP2A, p16INK4a and Ki-67 as biomarkers for the improved diagnosis of cervical intraepithelial lesion.
- p16/Ki-67 Dual-Stained Cytology Testing May Predict Postpartum Outcome in Patients with Abnormal Papanicolaou Cytology during Pregnancy.
- HPV E6/E7 RNA In Situ Hybridization Signal Patterns as Biomarkers of Three-Tier Cervical Intraepithelial Neoplasia Grade.
- Diagnostic value of HMGB1 immunostaining on cell blocks from residual liquid-based gynecologic cytology specimens.
- Detection and pathological value of papillomavirus DNA and p16(INK4A) and p53 protein expression in cervical intraepithelial neoplasia.
- Triaging borderline/mild dyskaryotic Pap cytology with p16/Ki-67 dual-stained cytology testing: cross-sectional and longitudinal outcome study.
- Impact of p16INK4a Immunohistochemistry Staining on Interobserver Agreement on the Diagnosis of Cervical Intraepithelial Neoplasia.
- Molecular fixative enables expression microarray analysis of microdissected clinical cervical specimens.
- Variability of Pathologists' Utilization of p16 and Ki-67 Immunostaining in the Diagnosis of Cervical Biopsies in Routine Pathology Practice and Its Impact on the Frequencies of Cervical Intraepithelial Neoplasia Diagnoses and Cytohistologic Correlations.
- [HPV testing in prevention of cervical cancer: practices and current trends].
- Detection of E6-AP as a potential therapeutic target in cervical specimen of HPV-infected women.
- Association of human papillomavirus L1 capsid protein with koilocytosis, expression of p16, and Ki-67, and its potential as a prognostic marker for cervical intraepithelial neoplasia.
- Eosinophilic dysplasia of the cervix associated with HPV 6 infection - case report and review of the literature.
- Gene amplification and immunohistochemical expression of ERBB2 and EGFR in cervical carcinogenesis. Correlation with cell-cycle markers and HPV presence.
- Expression of HPV-related biomarkers and grade of cervical intraepithelial lesion at treatment.
PubMed: CIN 1-LSIL
- A Cervical Abnormality Risk Prediction Model: Can We Use Clinical Information to Predict Which Patients With ASCUS/LSIL Pap Tests Will Develop CIN 2/3 or AIS?
- cervical intraepithelial neoplasia, low-grade dysplasia, mild dysplasia; +39 new citations
- HPV L1 capsid protein expression in squamous intraepithelial lesions of cervix uteri and its relevance to disease outcome.
- HPV vaccine protein L1 predicts disease outcome of high-risk HPV+ early squamous dysplastic lesions.
- Cytological surveillance compared with immediate referral for colposcopy in management of women with low grade cervical abnormalities: multicentre randomised controlled trial.
- Application of hTERC in thinprep samples with mild cytologic abnormality and HR-HPV positive.
- Incidence of cervical intraepithelial neoplasia grade 2 or worse in colposcopy-negative/human papillomavirus-positive women with low-grade cytological abnormalities.
- Diagnostic value of acetic acid comparing with conventional Pap smear in the detection of colposcopic biopsy-proved CIN.
- [Immunocytochemistry of p16(INK4a) and Ki-67 as adjunctive method for routine gynecological cytology of mild and moderate dysplasia.]
- Role of age stratification for colposcopy referral following initial diagnosis of mild dyskaryosis.
- Is this the end of the line for the moderate dyskaryotic smear?
- Allelic variations in CYP2D6 gene and susceptibility to cervical cancer.
- Cervical intraepithelial neoplasia (CIN) and Trichomonas vaginalis infection as revealed by polymerase chain reaction.
- Outcome analysis of 4 years' follow-up of patients referred for colposcopy with one smear showing mild dyskaryosis.
- Clinical significance of cytologic diagnosis of atypical squamous cells, cannot exclude high grade, in perimenopausal and postmenopausal women.
PubMed: CIN 2/3-HSIL
- Adjunct p16(INK4a) immunohistochemistry aids the detection of high-grade squamous intraepithelial lesions in endocervical curettage specimens.
- Effectiveness of the quadrivalent human papillomavirus vaccine against cervical dysplasia in Manitoba, Canada.
- Prevalence of cervical dysplasia in western Uttar Pradesh.
- Reducing Misclassification Bias in Cervical Dysplasia Risk Factor Analysis With p16-Based Diagnoses.
- Nucleotide polymorphisms of the human papillomavirus 16 E1 gene.
- HPV typing of high-grade dysplasia (CIN III) in cone biopsies of 38 HPV-vaccinated women.
- Cytomorphologic and clinical factors of having high-grade cervical intraepithelial neoplasia/invasive carcinoma in women with atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion (ASC-H) smears.
- A clinicopathologic study of vaginal intraepithelial neoplasia.
- Is the low-grade squamous intraepithelial lesion/atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion category associated with cervical intraepithelial neoplasia 2?
- Glucocorticoid-induced tumor necrosis factor receptor expression in patients with cervical human papillomavirus infection.
- Clinical significance of hTERC gene detection in exfoliated cervical epithelial cells for cervical lesions.
- Treatment options for high-grade squamous intraepithelial lesions.
- High-resolution anoscopy screening of HIV-positive MSM: longitudinal results from a pilot study.
- Anal cytology and p16 immunostaining for screening anal intraepithelial neoplasia in HIV-positive and HIV-negative men who have sex with men: a cross-sectional study.
- Clinicopathological Implications of Human Papilloma Virus (HPV) L1 Capsid Protein Immunoreactivity in HPV16-Positive Cervical Cytology.
AJSP: Table of Contents (latest issue):
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