Fullscreen
Loading...
 

Review Article: FNAC and Biobanking

By: Jana Sullinger, MD  On: Sun 22 of Apr., 2012 01:08 MDT  (2542 Reads)
Rating: star star star star star star star (7.00/10)
Review Article

Review Article
arrow Review Article: FNAC and Biobanking(external link)
by The Populist Cytologist
I thought this review article on Fine-Needle? Aspiration Cytology Is an Alternative Source of High Quality Archival Samples in Biobanking, written by Sani Abubakar Malami (© 2011), published in the ISRN Pathology was an interesting discussion. Those of us in the field of cytopathology are facing a challenge with respect to the reshaping of our field. This article describes potential uses of FNAC in biobanking, which currently hasn’t been utilized in any established fashion. The author concludes that in order “to accomplish the current requirements of the scientific community, archival FNAC tissue banks, like all other biobanks, need to address some essential challenges that include management strategies, consensus on standard operating procedures, appropriate design, harmonized and unique policies of utilization, and sustainability, all of them within the framework of the appropriate ethical, legal, and social considerations 2.”

Continue reading on The Populist Cytologist...(external link)

RESEARCH: Screening and cervical cancer cure: population based cohort study

By: Jana Sullinger, MD  On: Sat 03 of Mar., 2012 19:48 MST  (4091 Reads)
Rating: star star star star star star star star star half star (9.99/10)
Review Article

RESEARCH
Screening and cervical cancer cure: population based cohort study
BMJ 2012; 344 doi: 10.1136/bmj.e900 (Published 1 March 2012)
Cite this as: BMJ 2012;344:e900
Download article here(external link).

Rating: star star star star star (5.00/10)
Review Article

A preliminary study of the potential of tree classifiers in triage of high-grade squamous intraepithelial lesions. Anal Quant Cytol Histol. 2011 Jun;33(3):132-40
Authors: Karakitsos P, Pouliakis A, Meristoudis C, Margari N, Kassanos D, Kyrgiou M, Panayiotides JG, Paraskevaidis E

Abstract

OBJECTIVE: To investigate the potential value of tree classifiers for the triage of high-grade squamous intraepithelial lesions.

STUDY DESIGN: The dataset comprised 808 histologically confirmed cases having a complete range of the cytologic sample assessments--liquid-based cytology, reflex human papillomavirus (HPV) DNA test, E6/E7 HPV mRNA test, and p16 immunocytochemical examinations. Data include 488 histologically negative (cervical intraepithelial neoplasia CIN 1 and below) or clinically negative cases and 320 with histologic diagnosis of CIN 2 or worse. Cytologic diagnosis was made according to the criteria of the Bethesda System. Cases were classified in two groups according to histology: those with CIN 2 or worse and those with CIN 1 and below. Fifty percent were randomly selected as a training set and the remaining were as a test set.

RESULTS: Application of tree classifier on the test set gave correct classification of 66.9% for CIN 2 and above cases and 97.3% for CIN 1 and below, producing overall accuracy of 91.5%, outperforming cytologic diagnosis alone.

CONCLUSION: Application of tree classifiers, based on standard cytologic diagnosis and expression of studied biomarkers, produces improved classification results for cervical precancerous lesions and cancer diagnosis and

PMID: 21980616

Search Wiki Page

Exact match

CYTOPATHNET Polls

Do you plan to adopt the Bethesda Guidelines for Thyroid Cytology?






Code of Conduct

We comply with the HONcode standard for health trust worthy information:
verify here.

Theme: Tikinewt

TikiWiki assistant

Thank you for installing Tikiwiki!

LoginTo begin configuring Tiki, please login as admin.

The Tikiwiki CommunityTo learn more, visit: http://tiki.org.

Tikiwiki DocumentationFor help, visit http://doc.tiki.org.

Upcoming events

1)  Tue 12 of May, 2015
National Cytotechnology Day

Online users

124 online users

Search PubMed

PubMed Logo
Search PubMed:   

Shoutbox

kucingz2 points , 02:08 MDT, Tue 06 of May, 2014: http://goo.gl/3n9rax
kucingz2 points , 01:52 MDT, Mon 21 of Apr., 2014: [Link] [Link] [Link] [Link] [Link]
admin, 21:24 MST, Wed 22 of Feb., 2012: User registration enhancements made and more coming in future.
admin, 18:06 MST, Sun 29 of Jan., 2012: Site upgraded from 6.4 to 6.6.
admin, 21:56 MDT, Thu 06 of Oct., 2011: Not sure I totally understand question. Perhaps post to forums for feedback.

Random Image

thumbnail
possibleprostate adeno.jpg
Gallery: Urine Cytology

Google Search

 
cytopathnet.org
WWW

Site Language: English